| Product Name | Cat# | Clone# | Isotype | Applications | Reactivity | Unit/Size |
| Di-Methyl-Histone H3 (Lys27) Monoclonal Antibody | E-AB-22060 | 3I1 | IgG | WB* | Human,Mouse,Rat | 20μL, 60μL, 120μL, 200μL |
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Spec Sheet E-AB-22060 (PDF File)
| Synonyms | HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, HIST1H3F, H3FI, HIST1H3G, H3FH, HIST1H3H, H3FK, HIST1H3I, H3FF, HIST1H3J, H3FJ, Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/ |
| Swiss-Prot | P68431/Q71DI3/P84243 |
| Concentration | 1mg/mL |
| Host | Mouse |
| Immunogen | Synthetic Peptide |
| Purification Method | Protein A purification |
| Formulation | PBS with 0.02% sodium azide, 50% glycerol, pH7.4 |
| Storage | Store at -20?. Avoid freeze / thaw cycles. |
| Dilution | WB 1:1000-2000 |
Caution must be taken to avoid contact with skin or eyes. In such a case, rinse thoroughly at once with water. Do not ingest, inhale, or swallow. Seek medical attention immediately. Wear appropriate protective clothing such as laboratory overalls, safety glasses and gloves. It is strongly advised that this product should be handled by people who have been well trained in laboratory techniques and that it is handled with care pursuant to the principles of good laboratory practice. All chemicals are deemed potentially harmful. The vial is prone to fall over. Use caution, especially when the lid is off .
FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES.
* Remark Icon :
WB=Western Blotting, IP=Immunoprecipitation, IF=Immunofluorescence, IHC=Immunohistochemistory, IHC-p=Immunohistochemistory Paraffin, FCM=Flow Cytometry, CH=ChIP Assay
Manufactured by:Elabscience
