Product Description
| Product Name | Cat# | Clone# | Isotype | Applications | Reactivity | Unit/Size |
| 14-3-3 Monoclonal Antibody | E-AB-27413 | 954 | IgG1 | WB,IHC,IF,ELISA* | Human,Rat | 60μL, 120μL, 200μL |
Description
14-3-3 proteins interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms (gamma,epsilon,beta,zeta,sigma,theta,tau) that form multiple homo- and hetero- dimmers. 14-3-3 proteins display the highest expression levels in the brain,and have been implicated in several neurodegenerative diseases,including Alzheimer"s disease and amyotrophic lateral sclerosis. This antibody recognizes 14-3-3 tau (YWHAQ),eta (YWHAH),and zeta (YWHAZ),but not epsilon (YWHAE).
Spec Sheet E-AB-27413 (PDF File)
| Synonyms | 14 3 3,14 3 3 protein T cell,14 3 3 protein tau,14 3 3 protein theta,14-3-3 tau,HS1,Protein HS1,YWHAQ |
| Swiss-Prot | P27348 |
| Concentration | 1 mg/mL |
| Host | Mouse |
| Immunogen | Fusion protein of 14-3-3 |
| Purification Method | Protein G purification |
| Formulation | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Storage | Store at -20?. Avoid freeze / thaw cycles. |
| Dilution | WB 1:500-1:5000, IHC 1:50-1:500, IF 1:20-1:200 |
Caution must be taken to avoid contact with skin or eyes. In such a case, rinse thoroughly at once with water. Do not ingest, inhale, or swallow. Seek medical attention immediately. Wear appropriate protective clothing such as laboratory overalls, safety glasses and gloves. It is strongly advised that this product should be handled by people who have been well trained in laboratory techniques and that it is handled with care pursuant to the principles of good laboratory practice. All chemicals are deemed potentially harmful. The vial is prone to fall over. Use caution, especially when the lid is off .
FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES.
* Remark Icon :
WB=Western Blotting, IP=Immunoprecipitation, IF=Immunofluorescence, IHC=Immunohistochemistory, IHC-p=Immunohistochemistory Paraffin, FCM=Flow Cytometry, CH=ChIP Assay
Manufactured by:Elabscience
